Research Publications


Research Publications

Attipa, C., Beck, S., Lipscomb, V., English, K., Carvalho, S., Kiupel, M., & Peters, L. M. (2018). Aldosterone?producing adrenocortical carcinoma with myxoid differentiation in a cat. Veterinary clinical pathology. 2018 Sept. 

Bayton WA, Westgarth C, Scase T, Price DJ, Bexfield NH. Histopathological  frequency of feline hepatobiliary disease in the UK. J Small Anim Pract. J Small Anim Pract. 2018 Jul;59(7):404-410

Verin R, Cian F, Stewart J, Binanti D, MacNeill AL, Piviani M, Monti P, Baroni G, Le Calvez S, Scase TJ, Finotello R. Canine Clitoral Carcinoma: A Clinical, Cytologic, Histopathologic, Immunohistochemical, and Ultrastructural Study. Vet Pathol. 2018 Jul;55(4):501-509.

Milne E, Martinez Pereira Y, Muir C, Scase T, Shaw DJ, McGregor G, Oldroyd L, Scurrell E, Martin M, Devine C, Hodgkiss-Geere H. Immunohistochemical differentiation of reactive from malignant mesothelium as a diagnostic aid in canine pericardial disease. J Small Anim Pract. 2018 May;59(5):261-271.

Boss MK, Dewhirst MW, Sampaio RS, Bennett A, Tovmasyan A, Berman KG, Beaven AW, Rizzieri DA, Batinic-Haberle I, Hauck ML, Spasojevic I.  Potential for a novel manganese porphyrin compound as adjuvant canine lymphoma therapy.  Cancer Chemother Pharmacol. 2017 Aug;80(2):421-431.

Breheny CR, Fox V, Tamborini A, O’Halloran C, Robertson E, Cazzini P, Birn-Jeffery D, Henkin J, Schwartz T, Scase T, Powell R, Gunn-Moore D. Novel characteristics identified in two cases of feline cowpox virus infection. JFMSb Open Rep. 2017 Jul 11;3(2):2055116917717191.

Muir CF, Priestnall SL, Hibbert A, Brown C, Garden OA, Scase T. Prevalence of FoxP3(+) Cells Does Not Correlate With Ki67 Expression in Canine Diffuse Large B-cell Lymphoma. J Comp Pathol. 2017 Jul;157(1):15-22.

Latvala S, Jacobsen B, Otteneder MB, Herrmann A, Kronenberg S. Distribution of FcRn Across Species and Tissues. J Histochem Cytochem. 2017 Jun;65(6):321-333.

Beck, S., Gunawardena, P., Horton, D. L., Hicks, D. J., Marston, D. A., Ortiz-Pelaez, A., … & Núñez, A. Pathobiological investigation of naturally infected canine rabies cases from Sri Lanka. BMC Veterinary Research. 2017 Apr;13(1), 99.

Raftery AG, Berman KG. and Sutton DGM.  Severe eosinophilic cholangiohepatitis due to fluke infestation in a pony in Scotland.  Equine Vet Educ.  2017 Apr; 29(4):196-201.

Lugert S, Kremer T, Jagasia R, Herrmann A, Aigner S, Giachino C, Mendez-David I, Gardier AM, Carralot JP, Meistermann H, Augustin A, Saxe MD, Lamerz J, Duran-Pacheco G, Ducret A, Taylor V, David DJ, Czech C. Glypican-2 levels in cerebrospinal fluid predict the status of adult hippocampal neurogenesis. Sci Rep. 2017 Apr 25;7.

Macfarlane MJ, Macfarlane LL, Scase T, Parkin T, Morris JS. Use of neutrophil to lymphocyte ratio for predicting histopathological grade of canine mast cell tumours. Vet Rec. 2016 Nov 12;179(19):491.

Hutt JH, Dunn KA, Scase TJ, Shipstone MA. Pigmentary incontinence in the skin of the planum nasale from normal dogs. Vet Dermatol. 2016 Aug;27(4):324-325.

Gramer I, Killick D, Scase TJ, Chandry D, Marrington M, Blackwood L. Expression of VEGFR and PDGFR-?/-? in 187 canine nasal carcinomas. Vet Comp Oncol. 2016 Jun 9. doi: 10.1111/vco.12245. [Epub ahead of print]

O’Connell K, Leach J, Berman K, Knottenbelt C, Cazzini P.  What is your diagnosis? Salivary gland mass in a dog.  Vet Clin Pathol. 2016 Jun;45(2):389-90.

Georgina Harris, Samuel Beck, Birgit Parzefall, Stephen Cahalan, Ken Smith, Steven De Decker. Generalized vertebral abnormalities in a Rhodesian Ridgeback with a lysosomal storage disease. J Small Anim Pract. 2016 May;57;68-69.

Belluco S, Carnier P, Castagnaro M, Chiers K, Millanta F, Peña L, Pires I, Queiroga F, Riffard S, Scase TJ, Polton G. Immunohistochemical Labelling for Cyclo-oxygenase-2: Does the Positive Control Guarantee Standardized Results? J Comp Pathol. 2016 Feb-Apr;154(2-3):186-194.

Macfarlane L, Morris J, Pratschke K, Mellor D, Scase TJ, Macfarlane M, Mclauchlan G. Diagnostic value of neutrophil-lymphocyte and albumin-globulin ratios in canine soft tissue sarcoma. J Small Anim Pract. 2016 Mar;57(3):135-141

Van Stee LL, Boston SE, Singh A, Romanelli G, Rubio-Guzman A, Scase TJ. Outcome and Prognostic Factors for Canine Splenic Lymphoma Treated by Splenectomy (1995-2011). Vet Surg. 2015 Nov;44(8):976-982.

Hutt JH, Dunn KA, Scase TJ, Shipstone MA. A preliminary survey of the histopathological features of skin from the planum nasale and adjacent skin of dogs unaffected by dermatological or respiratory disease. Vet Dermatol. 2015 Oct;26(5):359-356

S Smith, RJ Naylor, EJ Knowles, TS Mair, SD Cahalan, D Fews, B Dunkel. Suspect acorn toxicity in nine horses. Equine Vet J. 2015 Sept;47(5);568-572.

Hughes K, Scase TJ, Foote AK. Estrogen Receptor and Signal Transducer and Activator of Transcription 3 Expression in Equine Mammary Tumors. Vet Pathol. 2015 Jul;52(4):631-634.

Newton JA, de Vicente F, Haugland SP, Scase TJ, Helm J. Extra-nodal subcutaneous Hodgkin’s-like lymphoma and subsequent regression in a cat. J Feline Med Surg. 2015 Jun;17(6):543-547.

Stefanello D, Buracco P, Sabattini S, Finotello R, Giudice C, Grieco V, Iussich S, Tursi M, Scase TJ, Di Palma S, Bettini G, Ferrari R, Martano M, Gattino F, Marrington M, Mazzola M, Elisabetta Vasconi M, Annoni M, Marconato L. Comparison of 2- and 3-category histologic grading systems for predicting the presence of metastasis at the time of initial evaluation in dogs with cutaneous mast cell tumors: 386 cases (2009-2014). J Am Vet Med Assoc. 2015 Apr 1;246(7):765-769.

SD Cahalan, R Cappello, A De Lahunta, BA Summers. A Novel Idiopathic Superficial Neocrotical Degeneration ad Atrophy in Young Adult Dogs. Vet Pathol. 2015 March;52(2);344-350.

Fontanella AN, Boss MK, Hadsell M, Zhang J, Schroeder T, Berman KG, Dewhirst MW, Chang S, Palmer GM.  Effects of high-dose microbeam irradiation on tumor microvascular function and angiogenesis.  Radiat Res. 2015 Feb;183(2):147-58.

Lesley HW Teo, Stephen D Cahalan, Livia Benigni, Zoe Halfacree. Oesophageal angioleiomyosarcoma in a cat. Feline Medicine and Surgery. 2014 Oct;16(10);846-852.

Krinke G, Herrmann A, Körner A, Landes C, Sauner F. Experience with examination of the spinal cord and periperal nervous system (PNS) in mice: A brief overview. Exp Toxicol Pathol. 2014 Sept;66(7):277-80.

Newman JC, Lustgarten M, Berman KG, Vivrette S, Redding WR.   Surgical treatment of synovial osteochondromatosis in the middle carpal joint of a pony.  Equine Vet Educ.  2014 Aug; 26(8):395–399.

Buness A, Roth A, Herrmann A, Schmitz O, Kamp H, Busch K, Suter L. Identification of metabolites, clinical chemistry markers and transcripts associated with hepatotoxicity. PLoS One. 2014 May;16;9(5).

Gómez Selgas A, Bexfield N, Scase TJ, Holmes MA, Watson P. J. Total serum bilirubin as a negative prognostic factor in idiopathic canine chronic hepatitis. Vet Diagn Invest. 2014 Mar;26(2):246-251.

Gómez Selgas A, Scase TJ, Foale RD. Unilateral squamous cell carcinoma of the renal pelvis with hydronephrosis in a cat. J Feline Med Surg. 2014 Feb;16(2):183-188.

Bray JP, Worley DR, Henderson RA, Boston SE, Mathews KG, Romanelli G, Bacon NJ, Liptak JM, Scase TJ. Hemipelvectomy: outcome in 84 dogs and 16 cats. A veterinary society of surgical oncology retrospective study. Vet Surg. 2014 Jan;43(1):27-37.

EM Horan, LVA Metcalfe, M Swarte, SD Cahalan, LM Katz. Pulmonary and hepatic eosinophilic granulomas and epistaxis in a horse suggestive of multi-systemic eosinophilic epitheliotropic disease. Equine Vet Ed. 2013 Dec;25(12)607-613.

Lucy VA Metcalfe, Peter J O’Brien, Stratos Papakonstantinou, Stephen D Cahalan, Hester McAllister, Vivienne E Duggan. Malignant melanoma in a grey horse: case presentation and review of equine melanoma treatment options. Irish Veterinary J. 2013 Nov;66(1);22.

S Lynch, Z Halfacree, I Desmas, SD Cahalan, EK Keenihan, CR Lamb. Pulmonary lipoma in a dog. J Small Anim Pract. 2013 Oct;54(10);555-558.

Dandrieux JR, Noble PJ, Scase TJ, Cripps PJ, German AJ. Comparison of a chlorambucil-prednisolone combination with an azathioprine-prednisolone combination for treatment of chronic enteropathy with concurrent protein-losing enteropathy in dogs: 27 cases (2007-2010). J Am Vet Med Assoc. 2013 Jun 15;242(12):1705-1714.

Kremer T, Jagasia R, Herrmann A, Matile H, Borroni E, Francis F, Kuhn HG, Czech C. Analysis of adult neurogenesis: evidence for a prominent “non-neurogenic” DCX-protein pool in rodent brain. PLoS One. 2013 May 14;8(5).

SD Cahalan, G Hick, A Rossiter, JJ Callanan. Fatal Prevotella oralis meningitis. J Small Anim Pract. 2013 March;54(3);153-155.

Charlesworth TM, Dunning M, Scase TJ, Anderson DM. Colonic vascular ectasia (angiodysplasia) in a juvenile dog. J Small Anim Pract. 2013 Jan;54(1):36-9.

Bommer NX, Hayes AM, Scase TJ, Gunn-Moore DA. Clinical features, survival times and COX-1 and COX-2 expression in cats with transitional cell carcinoma of the urinary bladder treated with meloxicam. J Feline Med Surg. 2012. 14(8): 527-533.

Kainzbauer C, Rushton J, Tober R, Scase T, Nell B, Sykora S, Brandt S. Bovine papillomavirus type 1 and Equus caballus papillomavirus 2 in equine squamous cell carcinoma of the head and neck in a Connemara mare. Equine Vet J. 2012, Jan;44(1):112-5.

Bexfield NH, Andres-Abdo C, Scase TJ, Constantino-Casas F, Watson PJ. Chronic hepatitis in the English springer spaniel: clinical presentation, histological description and outcome. Vet Rec. 2011 Oct 15;169(16):415.

SD Cahalan, L Sheridan, CR Akers, Ingrid Lorenz, Joe Cassidy. Atypical cutaneous actinobacillosis in young beef cattle. Vet Rec. 2012 Aug.

Tivers MS, Lipscomb VJ, Scase TJ, Priestnall SL, House AK, Gates H, Wheeler-Jones CP, Smith KC. Vascular Endothelial Growth Factor (VEGF) and VEGF Receptor Expression in Biopsy Samples of Liver from Dogs with Congenital Portosystemic Shunts. J Comp Pathol. 2012 Jul;147(1):55-61.

Micaela Zarelli, Robert Shiel, Barbara Gallagher, Cliona Skelly, Stephen Cahalan, Hester McAllister. Imaging diagnosis: CT findings in a dog with intracranial hemorrhage secondary to angiostrongylosis. J Veterinary Radiology & Ultrasound. 2012 July;53(4);420-423.

Matthew Campbell, Finnian Hanrahan, Oliviero L Gobbo, Michael E Kelly, Anna-Sophia Kiang, Marian M Humphries, Anh TH Nguyen, Ema Ozaki, James Keaney, Christoph W Blau, Christian M Kerskens, Stephen D Cahalan, John J Callanan, Eugene Wallace, Gerald A Grant, Colin P Doherty, Peter Humphries. Targeted suppression of claudin-5 decreases cerebral oedema and improves cognitive outcome following traumatic brain injury. J Nature Communications. 2012 May;(3):849.

Herrmann A, Tozzo E, Funk J. Semi-automated quantitive image analysis of podocyte desmin immunoreactivity as a sensitive marker for acute glomerular damage in the rat puromycin aminonucleoside nephrosis (PAN) model. Exp Toxicol Pathol. 2012 Jan;64(1-2)45-9.

Mair TS, Pearson GR, Scase TJ. Multiple small intestinal pseudodiverticula associated with lymphoma in three horses. Equine Vet J. 2011 Aug;43 Suppl 39:128-32.

Herrmann A, Hecht W, Herden C. Lissencephaly and microencephaly combined with hypoplasia of corpus callosum and cerebellum in a domestic cat. Tierarztl Prax Ausg K Kleintiere Heimtiere. 2011;39(2):116-20.

Beck S, Blunden T, Dyson S, Murray R. Are matrix and vascular changes involved in the pathogenesis of deep digital flexor tendon injury in the horse?. The Veterinary Journal. 2011 Aug;189(3), 289-295.

Watson PJ, Roulois A, Scase T, Holloway A, Herrtage ME. Characterization of chronic pancreatitis in English Cocker Spaniels. J Vet Intern Med. 2011 Jul-Aug;25(4):797-804.

Kamstock DA, Ehrhart EJ, Getzy DM, Bacon NJ, Rassnick KM, Moroff SD, Liu SM, Straw RC, McKnight CA, Amorim RL, Bienzle D, Cassali GD, Cullen JM, Dennis MM, Esplin DG, Foster RA, Goldschmidt MH, Gruber AD, Hellmén E, Howerth EW, Labelle P, Lenz SD, Lipscomb TP, Locke E, McGill LD, Miller MA, Mouser PJ, O’Toole D, Pool RR, Powers BE, Ramos-Vara JA, Roccabianca P, Ross AD, Sailasuta A, Sarli G, Scase TJ, Schulman FY, Shoieb AM, Singh K, Sledge D, Smedley RC, Smith KC, Spangler WL, Steficek B, Stromberg PC, Valli VE, Yager J, Kiupel M; American College of Veterinary Pathologists’ Oncology Committee. Recommended guidelines for submission, trimming, margin evaluation, and reporting of tumor biopsy specimens in veterinary surgical pathology. Vet Pathol. 2011 Jan;48(1):19-31.

Kiupel M, Webster JD, Bailey KL, Best S, DeLay J, Detrisac CJ, Fitzgerald SD, Gamble D, Ginn PE, Goldschmidt MH, Hendrick MJ, Howerth EW, Janovitz EB, Langohr I, Lenz SD, Lipscomb TP, Miller MA, Misdorp W, Moroff S, Mullaney TP, Neyens I,O’Toole D, Ramos-Vara J, Scase TJ, Schulman FY, Sledge D, Smedley RC, Smith K, W Snyder P, Southorn E, Stedman NL, Steficek BA, Stromberg PC, Valli VE, Weisbrode SE, Yager J, Heller J, Miller R. Proposal of a 2-tier histologic grading system for canine cutaneous mast cell tumors to more accurately predict biological behavior. Vet Pathol. 2011 Jan;48(1):147-55.

Valli VE, San Myint M, Barthel A, Bienzle D, Caswell J, Colbatzky F, Durham A, Ehrhart EJ, Johnson Y, Jones C, Kiupel M, Labelle P, Lester S, Miller M, Moore P, Moroff S, Roccabianca P, Ramos-Vara J, Ross A, Scase T, Tvedten H, Vernau W. Classification of canine malignant lymphomas according to the World Health Organization criteria. Vet Pathol. 2011 Jan;48(1):198-211.

Webster JD, Dennis MM, Dervisis N, Heller J, Bacon NJ, Bergman PJ, Bienzle D, Cassali G, Castagnaro M, Cullen J, Esplin DG, Peña L, Goldschmidt MH, Hahn KA, Henry CJ, Hellmén E, Kamstock D, Kirpensteijn J, Kitchell BE, Amorim RL, Lenz SD, Lipscomb TP, McEntee M, McGill LD, McKnight CA, McManus PM, Moore AS, Moore PF, Moroff SD, Nakayama H, Northrup NC, Sarli G, Scase T, Sorenmo K, Schulman FY, Shoieb AM, Smedley RC, Spangler WL, Teske E, Thamm DH, Valli VE, Vernau W, von Euler H, Withrow SJ, Weisbrode SE, Yager J, Kiupel M; American College of Veterinary Pathologists’ Oncology Committee. Recommended guidelines for the conduct and evaluation of prognostic studies in veterinary oncology. Vet Pathol. 2011 Jan;48(1):7-18.

Watson PJ, Archer J, Roulois AJ, Scase TJ, Herrtage ME. Observational study of 14 cases of chronic pancreatitis in dogs. Vet Rec. 2010 Dec 18;167(25):968-76.

Taylor F, Murphy S, Hoather T, Dobson J, Scase T. TSLC1 tumour-suppressor gene expression in canine mast cell tumours. Vet Comp Oncol. 2010 Dec;8(4):263-72.

Scase T, Brandt S, Kainzbauer C, Sykora S, Bijmholt S, Hughes K, Sharpe S, Foote A. Equus caballus papillomavirus-2 (EcPV-2): an infectious cause for equine genital cancer? Equine Vet J. 2010 Nov;42(8):738-45.

Watson PJ, Roulois AJ, Scase TJ, Irvine R, Herrtage ME. Prevalence of hepatic lesions at post-mortem examination in dogs and association with pancreatitis. J Small Anim Pract. 2010 Nov;51(11):566-72.

Buczinski S, Pinard J, Ferrouillet C, Veillette M. Echocardiographic findings in a goat with cor pulmonale secondary to chronic parasitic pneumonia. Schweiz Arch Tierheilkd. 2010 Feb;152(2):81-5.

Stell AJ, Dobson JM, Scase TJ, Catchpole B. Evaluation of variants of melanoma-associated antigen genes and mRNA transcripts in melanomas of dogs. Am J Vet Res. 2009 Dec;70(12):1512-20.

Hughes K, Scase TJ, Ward C, Polton GA. Vincristine overdose in a cat: clinical management, use of calcium folinate, and pathological lesions. J Feline Med Surg. 2009 Apr;11(4):322-5.

Matiasek LA, Platt SR, Adams V, Scase TJ, Keys D, Miller J, Adamo F, Long S, Matiasek K. Ki-67 and vascular endothelial growth factor expression in intracranial meningiomas in dogs. J Vet Intern Med. 2009 Jan-Feb;23(1):146-51.

Raffan E, McCallum A, Scase TJ, Watson PJ. Ascites is a negative prognostic indicator in chronic hepatitis in dogs. J Vet Intern Med. 2009 Jan-Feb;23(1):63-6.

Maglennon GA, Murphy S, Adams V, Miller J, Smith K, Blunden A, Scase TJ. Association of Ki67 index with prognosis for intermediate-grade canine cutaneous mast cell tumours. Vet Comp Oncol. 2008 Dec;6(4):268-74.

Donaldson D, Billson FM, Scase TJ, Sparkes AH, McConnell F, Mould JR, Adams V. Congenital hyposomatotropism in a domestic shorthair cat presenting with congenital corneal oedema. J Small Anim Pract. 2008 Jun;49(6):306-9.

Fews D, Scase TJ, Battersby IA. Leiomyosarcoma of the pericardium, with epicardial metastases and peripheral eosinophilia in a dog. J Comp Pathol. 2008 May;138(4):224-8.

Polton GA, Brearley MJ, Green LM, Scase TJ. Expression of E-cadherin in canine anal sac gland carcinoma and its association with survival. Vet Comp Oncol. 2007 Dec;5(4):232-8.

Watson PJ, Roulois AJ, Scase T, Johnston PE, Thompson H, Herrtage ME. Prevalence and breed distribution of chronic pancreatitis at post-mortem examination in first-opinion dogs. J Small Anim Pract. 2007 Nov;48(11):609-18.

Hollingsworth JW, Whitehead G, Berman KG, Tekippe EM, Gilmour MI, Larkin JE, Quackenbush J, Schwartz DA.  Genetic basis of murine antibacterial defense to streptococcal lung infection.  Immunogenetics. 2007 Sep;59(9):713-24.

Dobson JM, Scase TJ. Advances in the diagnosis and management of cutaneous mast cell tumours in dogs. J Small Anim Pract. 2007 Aug;48(8):424-31.

Hayes AM, Adams VJ, Scase TJ, Murphy S. Survival of 54 cats with oral squamous cell carcinoma in United Kingdom general practice. J Small Anim Pract. 2007 Jul;48(7):394-9.

Smith PM, Haughland SP, Jeffery ND. Brain abscess in a dog immunosuppressed using cyclosporin. Vet J. 2007 May;173(3):675-8.

Garantziotis S, Brass DM, Savov J, Hollingsworth JW, McElvania-TeKippe E, Berman K, Walker JK, Schwartz DA.  Leukocyte-derived IL-10 reduces subepithelial fibrosis associated with chronically inhaled endotoxin.  Am J Respir Cell Mol Biol. 2006 Dec;35(6):662-7.

Pinard J, Wagg CR, Girard C, Kiupel M, Bédard C. Histiocytic sarcoma in the tarsus of a cat. Vet Pathol. 2006 Nov;43(6):1014-7.

Burch LH, Yang IV, Whitehead GS, Chao FG, Berman KG, Schwartz DA.  The transcriptional response to lipopolysaccharide reveals a role for interferon-gamma in lung neutrophil recruitment.  Am J Physiol Lung Cell Mol Physiol. 2006 Oct;291(4):L677-82.

Walker JK1, Ahumada A, Frank B, Gaspard R, Berman K, Quackenbush J, Schwartz DA.  Multistrain genetic comparisons reveal CCR5 as a receptor involved in airway hyperresponsiveness.  Am J Respir Cell Mol Biol. 2006 Jun;34(6):711-8.

Cook DN1, Whitehead GS, Burch LH, Berman KG, Kapadia Z, Wohlford-Lenane C, Schwartz DA.  Spontaneous mutations in recombinant inbred mice: mutant toll-like receptor 4 (Tlr4) in BXD29 mice.  Genetics. 2006 Mar;172(3):1751-5.

Scase TJ, Edwards D, Miller J, Henley W, Smith K, Blunden A, Murphy S. Canine mast cell tumors: correlation of apoptosis and proliferation markers with prognosis. J Vet Intern Med. 2006 Jan-Feb;20(1):151-8.

Hollingsworth JW1, Chen BJ, Brass DM, Berman K, Gunn MD, Cook DN, Schwartz DA.  The critical role of hematopoietic cells in lipopolysaccharide-induced airway inflammation.  Am J Respir Crit Care Med. 2005 Apr 15;171(8):806-13.

Cook DN1, Wang S, Wang Y, Howles GP, Whitehead GS, Berman KG, Church TD, Frank BC, Gaspard RM, Yu Y, Quackenbush J, Schwartz DA.  Genetic regulation of endotoxin-induced airway disease.  Genomics. 2004 Jun;83(6):961-9.

Savov JD1, Brass DM, Berman KG, McElvania E, Schwartz DA.  Fibrinolysis in LPS-induced chronic airway disease.  Am J Physiol Lung Cell Mol Physiol. 2003 Oct;285(4):L940-8.

Whitehead GS1, Walker JK, Berman KG, Foster WM, Schwartz DA.  Allergen-induced airway disease is mouse strain dependent. Am J Physiol Lung Cell Mol Physiol. 2003 Jul;285(1):L32-42.

Book chapters:
  • “How to make a diagnosis” Scase TJ and Dobson JM, in BSAVA Manual of Canine and Feline Oncology, 3rd edition.